Do you need a business permit for an online (business)comic strip series?

I want to thank everyone who answered my previous questions.
Your responses were helpful and informative.

You may want to check with your city's business license department. Where I presently live, any home based business is required to have a city issued business license. But, where I used to live, certain businesses (i.e. service businesses with no client visitation) were exempt.

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